KEGG   Trypanosoma brucei brucei: Tb11.02.4080
Entry
Tb11.02.4080      CDS       T01013                                 
Name
(RefSeq) lanosterol 14-alpha-demethylase
  KO
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Organism
tbr  Trypanosoma brucei brucei
Pathway
tbr00100  Steroid biosynthesis
tbr01100  Metabolic pathways
tbr01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:tbr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    Tb11.02.4080
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:tbr00199]
    Tb11.02.4080
Enzymes [BR:tbr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154  sterol 14alpha-demethylase
     Tb11.02.4080
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.36  sterol 14alpha-demethylase (ferredoxin)
     Tb11.02.4080
Cytochrome P450 [BR:tbr00199]
 Cytochrome P450, animal type
  CYP51 family
   Tb11.02.4080
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 3665105
NCBI-ProteinID: XP_828695
UniProt: Q385E8
Structure
Position
11
AA seq 481 aa
MLLEVAIFLLTALALYSFYFVKSFNVTRPTDPPVYPVTVPILGHIIQFGKSPLGFMQECK
RQLKSGIFTINIVGKRVTIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPY
PRMREQLNFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIINTAC
QCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSARCHEARTELQKIL
SEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMSLHEVCGMIVAAMFAGQHTSSITT
TWSMLHLMHPANVKHLEALRKEIEEFPAQLNYNNVMDEMPFAERCARESIRRDPPLLMLM
RKVMADVKVGSYVVPKGDIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVH
KCIGQKFGLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRKAAA
A
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgttgcttgaagttgccattttcttactaacagcacttgcgttgtattcgttttacttt
gtcaaatcattcaatgtcacgaggccgacagatccaccagtgtatcctgtcaccgtaccc
attcttggacacattatacagtttggaaaaagccctcttggcttcatgcaggaatgcaag
cgtcaattgaagtcaggcatttttaccattaacatcgtgggtaagagggtgaccatcgtt
ggcgatccccacgaacacagccgcttctttttgcctcgtaacgaggtattgtcaccgcgg
gaagtgtacagttttatggtgcccgtgtttggtgagggggttgcatatgctgccccgtac
ccaaggatgcgtgagcaactcaactttcttgcggaggaattaaccatcgccaagtttcag
aacttcgtccccgccattcagcacgaggtgcgcaagtttatggcggccaactgggataag
gacgagggggaaatcaatttgctggaggactgcagcacaatgattattaataccgcttgt
cagtgtttatttggggaggacctgcggaagcggctcgatgcgcgtaggttcgcgcaactt
ctggcgaagatggaaagcagtttaatccctgcggctgtgttcctgcccatcttgctgaag
ttaccactcccacaatctgcccgctgccacgaggcacgtaccgaactgcagaaaattctc
agtgagattatcattgctcgaaaggaggaggaagtcaacaaggacagctctacatccgat
cttctctcaggccttctcagtgccgtctaccgcgacggaactcccatgtccctacacgag
gtatgtggcatgatcgtggctgccatgttcgctggtcagcacacttcatccatcaccact
acgtggtctatgctgcatcttatgcacccagcaaacgtaaagcacctggaggcgttacgc
aaggaaattgaggagttccccgctcaactcaattacaataatgtgatggacgaaatgccc
tttgcggagcgttgcgcccgcgagtccattcgccgtgacccgccactcctcatgctgatg
cgcaaggtaatggccgatgtaaaggttgggtcgtatgttgtaccaaaaggcgatatcatc
gcatgttcaccgcttctctctcatcatgacgaggaggcctttccagagccgaggcggtgg
gatccggagagagacgagaaggttgaaggtgcttttatcggcttcggtgccggagtgcac
aagtgcattggtcaaaaatttggacttctgcaggtgaaaacaattcttgccacagctttc
cgaagctatgatttccagctattacgggatgaagtgccggaccctgactatcacacaatg
gttgtcggaccaactgcgtcacagtgccgtgtgaaatacatccggcggaaggcggcagct
gcttag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (3)   
   KEGG MODULE (3)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (9)   
   PDB (9)   
Protein domain (1)   
   Pfam (1)   
All databases (68)   

Download RDF
DBGET integrated database retrieval system